Further Reassurance for COVID-19 Vaccination Safety During Pregnancy
NEJM Journal Watch (March 29, 2022) – Two studies showed no evidence of adverse obstetrical or perinatal outcomes.
The initial COVID-19 vaccine trials did not include pregnant women, which led to questions about vaccine safety in pregnancy, but early studies were reassuring regarding the safety of mRNA vaccines in pregnant women. Findings from two new studies reinforce those data.
In one study, researchers identified 158,000 singleton pregnancies from Sweden and Norway in linked pregnancy and vaccination databases. In another study, similar linkage was performed for 98,000 Canadian pregnancies. In both studies, vaccination during pregnancy ā usually with mRNA vaccines given during the second or third trimester ā occurred in about 20% of women. Women who had been vaccinated prior to pregnancy were excluded.
Further Reassurance for COVID-19 Vaccination Safety During Pregnancy (jwatch.org)